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Last Updated: September 30, 2020

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Patent: 7,901,453

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Summary for Patent: 7,901,453
Title:Coated implantable medical device
Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract, and at least one layer 18 of an immunosuppressive agent posited over at least one surface of the structure 12. Optionally, the device 10 can include at least one porous, preferably polymeric layer 20 posited over the layer 18 of immunosuppressive agent, and can alternatively or additionally include at least one coating layer 16 posited on one surface of the structure 12, the at least one layer 18 of immunosuppressive agent being posited in turn on at least a portion of the coating layer 16. The porous layer 20 and the coating layer 16 each provide for the controlled release of the bioactive material from the device 10. The structure 12 is preferably configured as a coronary stent. The polymer of the porous layer 20 is preferably applied by vapor or plasma deposition. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative which is deposited without solvents, heat or catalysts, but rather by condensation of a monomer vapor.
Inventor(s): Ragheb; Anthony O. (West Lafayette, IN), Fearnot; Neal E. (West Lafayette, IN), Voorhees, III; William D. (West Lafayette, IN), Kozma; Thomas G. (Canton, GA), Bates; Brian L. (Bloomington, IN), Osborne; Thomas A. (Bloomington, IN)
Assignee: Cook Incorporated (Bloomington, IN) MED Institute, Inc. (West Lafayette, IN)
Application Number:11/932,113
Patent Claims:see list of patent claims

Details for Patent 7,901,453

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Novartis SIMULECT basiliximab VIAL; SINGLE-USE 103764 001 1998-05-12   Start Trial Cook Incorporated (Bloomington, IN) MED Institute, Inc. (West Lafayette, IN) 2016-05-16 RX search
Novartis SIMULECT basiliximab VIAL; SINGLE-USE 103764 002 1998-05-12   Start Trial Cook Incorporated (Bloomington, IN) MED Institute, Inc. (West Lafayette, IN) 2016-05-16 RX search
Biogen ZINBRYTA daclizumab INJECTABLE;INJECTION 761029 001 2017-05-26   Start Trial Cook Incorporated (Bloomington, IN) MED Institute, Inc. (West Lafayette, IN) 2016-05-16 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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