➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

Harvard Business School
Merck
AstraZeneca
Boehringer Ingelheim
Dow
Johnson and Johnson

Last Updated: September 24, 2020

DrugPatentWatch Database Preview

Patent: 7,892,749

➤ Get the DrugPatentWatch Daily Briefing
» See Plans and Pricing

« Back to Dashboard

Summary for Patent: 7,892,749
Title:Methods for differentiating and monitoring parathyroid and bone status related diseases
Abstract: The present invention relates to novel methods and devices for differentiating in a patient parathyroid diseases, such as hyperparathyroidism and related bone diseases, from normal or non-disease states. One detects whole or non-fragmented (1 to 84) parathyroid hormone in a biological sample and also a large non-whole parathyroid hormone peptide fragment that can function as a parathyroid hormone antagonist. By either comparing values or using independently the value of either the large non-whole parathyroid hormone peptide fragment, the whole parathyroid hormone, or the combination of these values one is able to differentiate parathyroid and bone related disease states, as well as differentiate such states from normal states In specific embodiments, the present invention relates to isolated antibodies, including polyclonal antibodies, that specifically bind to a three-dimensional epitope of a parathyroid hormone (PTH) in PTH.sub.1-8 as part of whole PTH, wherein at least four amino acids in PTH.sub.1-8 are part of the reactive portion of the isolated antibodies, and the isolated antibodies do not specifically bind to a non-(1-84) PTH fragment, e.g., a PTH.sub.7-84 fragment. Therapeutic compositions and kits comprising the isolated antibodies are also provided.
Inventor(s): Cantor; Thomas L. (El Cajon, CA), Gao; Ping (San Diego, CA)
Assignee: Scantibodies Laboratory, Inc. (Santee, CA)
Application Number:10/760,091
Patent Claims:see list of patent claims

Details for Patent 7,892,749

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Scantibodies Laboratory, Inc. (Santee, CA) 2019-01-14 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Scantibodies Laboratory, Inc. (Santee, CA) 2019-01-14 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Scantibodies Laboratory, Inc. (Santee, CA) 2019-01-14 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Scantibodies Laboratory, Inc. (Santee, CA) 2019-01-14 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

McKinsey
Boehringer Ingelheim
Johnson and Johnson
Medtronic
Harvard Business School
Dow

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.