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Last Updated: September 29, 2020

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Patent: 7,871,790

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Summary for Patent: 7,871,790
Title:Anthrax bioassays and methods of treating and diagnosing anthrax infection
Abstract: Based on the observation that exposure of cells or animals to anthrax lethal toxin results in activation of the intracellular enzyme caspase-1/IL-1 converting enzyme (ICE), which, in turn, leads to production and extracellular release of the cytokine substrates of ICE: interleukin 1 beta (IL-1.beta.) and interleukin 18 (IL-18), disclosed herein are bioassays that can be used to determine the efficacy of a potential anthrax therapeutic agent and for screening test agents to identify anthrax therapeutic agents. Also disclosed herein are methods of diagnosing and treating anthrax infection.
Inventor(s): Frucht; David M. (Vienna, VA), Cordoba-Rodriguez; Ruth (Baltimore, MD)
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, DC) N/A (N/A)
Application Number:11/071,799
Patent Claims:see list of patent claims

Details for Patent 7,871,790

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Emergent Biodefense Operations Lansing, Llc BIOTHRAX bacillus anthracis INJECTION, SUSPENSION 103821 1 1970-11-04   Start Trial The United States of America as represented by the Department of Health and Human Services (Washington, DC) N/A (N/A) 2024-03-02 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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