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Last Updated: August 10, 2020

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Patent: 7,838,239

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Summary for Patent: 7,838,239
Title:Methods regarding enhanced T-cell receptor-mediated tumor necrosis factor superfamily mRNA expression in peripheral blood leukocytes in patients with crohn\'s disease
Abstract: A method is disclosed for determining whether a human having Crohn\'s disease is likely to respond to a therapy targeting a TNFSF member or a cytokine by measuring the level of certain mRNAs in response to a stimulus. A method of evaluating the effectiveness of a Crohn\'s disease therapy in a human is also disclosed. Furthermore, a method of screening compounds for use in the treatment of Crohn\'s disease is disclosed. A method of monitoring the disease state over time in Crohn\'s disease patients is also disclosed.
Inventor(s): Mitsuhashi; Masato (Irvine, CA), Targan; Stephan R. (Santa Monica, CA)
Assignee: Hitachi Chemical Co., Ltd. (Tokyo, JP) Hitachi Chemical Research Center, Inc. (Irvine, CA) Cedars-Sinai Medical Center (Los Angeles, CA)
Application Number:12/296,425
Patent Claims:see list of patent claims

Details for Patent 7,838,239

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial Hitachi Chemical Co., Ltd. (Tokyo, JP) Hitachi Chemical Research Center, Inc. (Irvine, CA) Cedars-Sinai Medical Center (Los Angeles, CA) 2026-04-07 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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