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Last Updated: October 1, 2020

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Patent: 7,833,525

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Summary for Patent: 7,833,525
Title:Crystals of whole antibodies and fragments thereof and methods for making and using them
Abstract: This invention relates to crystals of whole antibodies and fragments thereof, and formulations and compositions comprising such crystals. More particularly, methods are provided for the crystallization of high concentrations of whole antibodies, and fragments thereof, in large batches, and for the preparation of stabilized whole antibody crystals for use alone, or in dry or slurry formulations or compositions. This invention also relates to methods for stabilization, storage and delivery of biologically active whole antibody crystals.
Inventor(s): Shenoy; Bhami (Woburn, MA), Govardhan; Chandrika P. (Lexington, MA), Yang; Mark X. (Newton, MA), Margolin; Alexey L. (Newton, MA)
Assignee:
Application Number:10/034,950
Patent Claims:see list of patent claims

Details for Patent 7,833,525

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial 2020-12-28 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Mallinckrodt
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Baxter
Johnson and Johnson
Express Scripts
McKesson

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