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Last Updated: December 15, 2019

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Patent: 7,825,223

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Summary for Patent: 7,825,223
Title:Methods of purifying anti A .beta. antibodies
Abstract: The present application provides methods of purifying A.beta. binding proteins having a Fc region, for example, anti-A.beta. antibodies or antibody fusions, by adsorbing the A.beta. binding protein to a Fc binding agent, such as, for example, Protein A or Protein G, followed by a wash with a divalent cation salt buffer to remove impurities and subsequent recovery of the adsorbed A.beta. binding protein. The present application also features methods of eluting the purified A.beta. binding protein as well as the incorporation of the methods within a purification train. Kits comprising components for carrying out the methods and instructions for use are also provided.
Inventor(s): Godavarti; Ranganathan (Burlington, MA), Iskra; Timothy (Derry, NH)
Assignee: Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ)
Application Number:11/454,772
Patent Claims:see list of patent claims

Details for Patent 7,825,223

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ) 2025-06-17 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ) 2025-06-17 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ) 2025-06-17 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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