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Last Updated: October 1, 2020

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Patent: 7,820,799

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Summary for Patent: 7,820,799
Title:Methods of purifying Fc region containing proteins
Abstract: The present application provides methods of purifying polypeptides having a Fc region, for example, antibodies or antibody fusions, by adsorbing the polypeptides to a Fc binding agent, such as, for example, Protein A or Protein G, followed by a wash with a divalent cation salt buffer to remove impurities and subsequent recovery of the adsorbed polypeptides. The present application also features methods of eluting the purified polypeptide as well as the incorporation of the methods within a purification train. Kits comprising components for carrying out the methods and instructions for use are also provided.
Inventor(s): Godavarti; Ranganathan (Burlington, MA), Iskra; Timothy (Derry, NH)
Assignee: Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ)
Application Number:11/455,203
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,820,799
Patent Claims:see list of patent claims

Details for Patent 7,820,799

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ) 2025-06-17 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ) 2025-06-17 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Janssen Alzheimer Immunotherapy (Little Island, County Cork, IE) Wyeth LLC (Madison, NJ) 2025-06-17 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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