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Generated: September 18, 2019

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Patent: 7,803,810

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Summary for Patent: 7,803,810
Title:Inhibitors
Abstract: Compounds of formula (I), combinations and uses thereof for disease therapy, ##STR00001## or a pharmaceutically acceptable salt or solvate thereof, including all tautomers, stereoisomers and polymorphs thereof wherein: R.sup.1 represents C.sub.2-8alkyl; C.sub.2-8alkenyl; --(C.sub.1-6alkyl)-aryl; --(C.sub.1-6alkyl)-heteroaryl; --(C.sub.1-6alkyl)-carbocyclyl; --(C.sub.1-6alkyl)-heterocyclyl; -aryl; -heteroaryl; -carbocyclyl or -heterocyclyl; wherein said aryl or heteroaryl groups may be optionally substituted by one or more substituents selected from, C.sub.1-4alkyl, C.sub.1-4-fluoroalkyl, C.sub.1-4alkoxy, C.sub.1-4-fluoroalkoxy, hydroxy, --SO.sub.2(C.sub.1-4alkyl), --SO.sub.2N(C.sub.1-4alkyl)(C.sub.1-4alkyl), --SOC.sub.1-4alkyl, --SOC.sub.3-6cycloalkyl --C(O)O(C.sub.1-4alkyl), benzyloxy and phenyl; and wherein said carbocyclyl and heterocyclyl groups may be optionally substituted by one or more substituents selected from --C.sub.1-4 alkyl, --C.sub.1-4 alkoxy, hydroxyl, halogen and oxo; R.sup.2 represents H; C.sub.1-4alkyl or halogen; R.sup.3 represents H; C.sub.1-4alkyl or halogen; and R.sup.4 represents H; C.sub.1-4alkyl or halogen.
Inventor(s): Ramsbeck; Daniel (Halle/Saale, DE), Heiser; Ulrich (Halle/Saale, DE), Buchholz; Mirko (Halle/Saale, DE), Niestroj; Andre J. (Sennewitz, DE)
Assignee: Probiodrug AG (Halle/Saale, DE)
Application Number:12/045,163
Patent Claims:see list of patent claims

Details for Patent 7,803,810

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07   Try a Free Trial Probiodrug AG (Halle/Saale, DE) 2028-03-09 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07   Try a Free Trial Probiodrug AG (Halle/Saale, DE) 2028-03-09 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07   Try a Free Trial Probiodrug AG (Halle/Saale, DE) 2028-03-09 RX Orphan search
Biogen Idec TYSABRI natalizumab VIAL; SINGLE-USE 125104 001 2004-11-23   Try a Free Trial Probiodrug AG (Halle/Saale, DE) 2028-03-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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