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Last Updated: June 1, 2020

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Patent: 7,803,376

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Summary for Patent: 7,803,376
Title:Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
Inventor(s): Velardi; Andrea (Perugia, IT), Romagne; Francois (La Ciotat, FR)
Assignee: Innate Pharma S.A. (Marseilles, FR)
Application Number:10/897,624
Patent Claims:see list of patent claims

Details for Patent 7,803,376

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial Innate Pharma S.A. (Marseilles, FR) 2023-07-24 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial Innate Pharma S.A. (Marseilles, FR) 2023-07-24 RX search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07   Start Trial Innate Pharma S.A. (Marseilles, FR) 2023-07-24 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07   Start Trial Innate Pharma S.A. (Marseilles, FR) 2023-07-24 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07   Start Trial Innate Pharma S.A. (Marseilles, FR) 2023-07-24 RX Orphan search
Genentech Inc RITUXAN HYCELA rituximab; hyaluronidase (human recombinant) SOLUTION;SUBCUTANEOUS 761064 001 2017-06-22   Start Trial Innate Pharma S.A. (Marseilles, FR) 2023-07-24 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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