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Last Updated: September 28, 2020

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Patent: 7,790,680

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Summary for Patent: 7,790,680
Title:Stable pharmaceutical composition containing factor VIII
Abstract: The invention relates to a stable solid pharmaceutical composition comprising factor VIII. Such a composition is devoid of amino acids and comprises: (a) factor VIII; (b) a surfactant; (c) calcium chloride; (d) sucrose; (e) sodium chloride; (f) trisodium citrate; and (g) a buffer devoid of amino acids; and has a pH from 6 to 8 prior to lyophilization and after reconstitution in water for injection. The invention also relates to the liquid pharmaceutical composition obtainable after dilution of said stable solid pharmaceutical composition with sterile water optionally containing sodium chloride.
Inventor(s): White; Mary (Wrexham, GB), Webb; Paul (Wrexham, GB)
Assignee: Ipsen Pharma S.A.S. (Paris, FR)
Application Number:10/507,956
Patent Claims:see list of patent claims

Details for Patent 7,790,680

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial Ipsen Pharma S.A.S. (Paris, FR) 2022-03-26 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial Ipsen Pharma S.A.S. (Paris, FR) 2022-03-26 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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AstraZeneca
Medtronic
McKesson

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