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Last Updated: September 26, 2020

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Patent: 7,763,256

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Summary for Patent: 7,763,256
Title:Compositions and methods for suppressing fibrocytes and for detecting fibrocyte differentiation
Abstract: The present invention relates to the ability of SAP to suppress fibrocytes. It also relates to the ability of IL-12, laminin-1, cross-linked IgG and IgG aggregates to suppress fibrocytes. Methods and compositions for suppressing fibrocytes using these proteins are provided. These methods are useful in a variety of applications including treatment and prevention of fibrosing diseases such as scleroderma, pulmonary fibrosis and asthma. Finally, the invention includes assays for detecting the ability of various agents to modulate differentiation into fibrocytes. Such assays may also be used to diagnose scleroderma, pulmonary fibrosis, or other fibrosing diseases.
Inventor(s): Gomer; Richard (Houston, TX), Pilling; Darrell (Pearland, TX)
Assignee: William Marsh Rice University (Houston, TX)
Application Number:11/535,636
Patent Claims:see list of patent claims

Details for Patent 7,763,256

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31   Start Trial William Marsh Rice University (Houston, TX) 2022-12-23 RX search
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31   Start Trial William Marsh Rice University (Houston, TX) 2022-12-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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