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Generated: July 18, 2019

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Patent: 7,741,098

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Summary for Patent: 7,741,098
Title:Production of eukaryotic proteins and nucleic acid molecules in C. elegans
Abstract: Plasmid vectors for expression in Caenorhabditis elegans harbouring a heat inducible promoter nucleotide sequence, a synthetic intron nucleotide sequence optionally containing a Shine-Dalgarno sequence for efficient shuttling between C. elegans and E. coli, optionally a nucleotide sequence coding for a nuclear localisation signal or secretion signal, a nucleotide sequence coding for a recognizable tag, optionally a nucleotide sequence coding for a fluorescent protein, a nucleotide sequence coding for a protease cleavage site, a multiple cloning site containing a nucleotide sequence coding for an eukaryotic, such as human, protein or a nucleic acid molecule and a nucleotide sequence coding for termination of translation, are described. Methods of particularly large scale production of eukaryotic, such as human, proteins and nucleic acid molecules in nematodes are also described.
Inventor(s): Sauer; Uwe H (Umea, SE), Tuck; Simon (Umea, SE)
Assignee: neXyte AB (Umea, SE)
Application Number:10/496,767
Patent Claims:see list of patent claims

Details for Patent 7,741,098

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04 ➤ Try a Free Trial neXyte AB (Umea, SE) ➤ Try a Free Trial RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04 ➤ Try a Free Trial neXyte AB (Umea, SE) ➤ Try a Free Trial RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04 ➤ Try a Free Trial neXyte AB (Umea, SE) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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