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Harvard Business School
Boehringer Ingelheim

Last Updated: November 29, 2021

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Patent: 7,736,653

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Summary for Patent: 7,736,653
Title:Pharmaceutical composition comprising an immunoglobulin Fc region as a carrier
Abstract: Disclosed is a novel use of an immunoglobulin Fc fragment, and more particularly, a pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier. The pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier remarkably extends the serum half-life of a drug while maintaining the in vivo activity of the drug at relatively high levels. Also, when the drug is a polypeptide drug, the pharmaceutical composition has less risk of inducing immune responses compared to a fusion protein of the immunoglobulin Fc fragment and a target protein, and is thus useful for developing long-acting formulations of various polypeptide drugs.
Inventor(s): Kim; Young Min (Yongin-si, KR), Song; Dac Hae (Geumcheon-gu, KR), Jung; Sung Youb (Suwon-si, KR), Kim; Chang Hwan (Suwon-si, KR), Choi; In Young (Seongnam-si, KR), Kwon; Se Chang (Gwangjin-gu, KR), Lee; Gwan Sun (Songpa-gu, KR)
Assignee: Hanmi Pharm. Co., Ltd (Hwaseong-si, KR)
Application Number:10/535,231
Patent Claims:see list of patent claims

Details for Patent 7,736,653

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Microbix Biosystems Inc. KINLYTIC urokinase For Injection 021846 1978-01-16 ⤷  Try it Free 2023-11-13
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2023-11-13
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Try it Free 2023-11-13
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Express Scripts
Johnson and Johnson

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