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Last Updated: October 1, 2020

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Patent: 7,736,653

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Summary for Patent: 7,736,653
Title:Pharmaceutical composition comprising an immunoglobulin Fc region as a carrier
Abstract: Disclosed is a novel use of an immunoglobulin Fc fragment, and more particularly, a pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier. The pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier remarkably extends the serum half-life of a drug while maintaining the in vivo activity of the drug at relatively high levels. Also, when the drug is a polypeptide drug, the pharmaceutical composition has less risk of inducing immune responses compared to a fusion protein of the immunoglobulin Fc fragment and a target protein, and is thus useful for developing long-acting formulations of various polypeptide drugs.
Inventor(s): Kim; Young Min (Yongin-si, KR), Song; Dac Hae (Geumcheon-gu, KR), Jung; Sung Youb (Suwon-si, KR), Kim; Chang Hwan (Suwon-si, KR), Choi; In Young (Seongnam-si, KR), Kwon; Se Chang (Gwangjin-gu, KR), Lee; Gwan Sun (Songpa-gu, KR)
Assignee: Hanmi Pharm. Co., Ltd (Hwaseong-si, KR)
Application Number:10/535,231
Patent Claims:see list of patent claims

Details for Patent 7,736,653

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Hanmi Pharm. Co., Ltd (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Hanmi Pharm. Co., Ltd (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Hanmi Pharm. Co., Ltd (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Hanmi Pharm. Co., Ltd (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Hanmi Pharm. Co., Ltd (Hwaseong-si, KR) 2023-11-13 RX search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Hanmi Pharm. Co., Ltd (Hwaseong-si, KR) 2023-11-13 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 7,736,653

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Express Scripts
Baxter
Johnson and Johnson
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Mallinckrodt

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