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Last Updated: September 30, 2020

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Patent: 7,723,108

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Summary for Patent: 7,723,108
Title:Soft tissue processing
Abstract: The present invention is a process for preparing soft tissue such as tendons, ligaments, cartilage, fascia, dermis, human valves and human veins for implant in a human and removes cellular components and forms an decellular matrix having as major components collagens and elastins while sterilizing the tissue. The process comprises the following steps: (1) isolating from a suitable donor a desired soft tissue sample of the biological material; (2) processing and decellularizing the soft tissue including inspection for visual defects, trimming and soaking the tissue in a detergent depending on whether the tissue is fascia or dermis and rinsing same with sterile water; (3) sterilizing the soft tissue in a vacuum and soaking the tissue in an antibiotic composition or peracetic acid depending on whether the soft tissue is fascia or dermis and rinsing same; (4) processing the tissue by cutting the tissue to size and perforating the tissue; and (5) dipping the tissue in 70% ethanol and packaging the tissue.
Inventor(s): Truncale; Katherine Gomes (Hillsborough, NJ), Cartmell; Jeffrey Stuart (Freehold, NJ), Syring; Carina (Basel, CH), Von Versen; Rudiger (Basdorf, DE), Ngo; Manh-Dan (Rochester, NY)
Assignee: Musculoskeletal Transplant Foundation (Edison, NJ)
Application Number:11/375,026
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,723,108
Patent Claims:see list of patent claims

Details for Patent 7,723,108

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Hlthcare TRASYLOL aprotinin INJECTABLE;INJECTION 020304 001 1994-02-07   Start Trial Musculoskeletal Transplant Foundation (Edison, NJ) 2025-03-16 DISCN search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial Musculoskeletal Transplant Foundation (Edison, NJ) 2025-03-16 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial Musculoskeletal Transplant Foundation (Edison, NJ) 2025-03-16 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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