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Generated: July 22, 2019

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Patent: 7,714,276

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Summary for Patent: 7,714,276
Title:Methods for direct biomolecule identification by matrix-assisted laser desorption ionization (MALDI) mass spectrometry
Abstract: The present invention relates to the use of post source decay (PSD) or collision induced dissociation (CID) direct tissue (DT) MALDI-TOF or DT-MALDI-TOF-TOF mass spectrographic identification of biological molecules in a tissue or cellular sample without the need for further protein extraction. This method provides for studying cells or tissues by direct tissue MALDI (DT-MALDI), thereby substituting in situ protein release for further protein extraction. Mass/intensity data was processed with Mascot.COPYRGT. software interrogation of the NCBI database. These results are proof of principle that DT-MALDI, combined with bioinformatics, can directly identify proteins in cells and tissues from their mass spectra.
Inventor(s): Pevsner; Paul (New York, NY), Naftolin; Frederick (Woodbridge, CT), Miller; Douglas C. (Delle Mead, NJ), Hillman; Dean (New Hyde Park, NY), Stall; Brian K. (Bedford, NH), Wishnie; Steven M. (Columbia, MD)
Assignee: New York University (New York, NY)
Application Number:11/541,380
Patent Claims:see list of patent claims

Details for Patent 7,714,276

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Try a Free Trial New York University (New York, NY) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 7,714,276

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 2007041520 Apr 12, 2007
World Intellectual Property Organization (WIPO) 2007041520 Apr 30, 2009
World Intellectual Property Organization (WIPO) 2007041520 Aug 30, 2007
United States of America 2007114375 May 24, 2007
United States of America 2011062320 Mar 17, 2011
Country Patent Number Publication Date

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