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Generated: July 18, 2019

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Patent: 7,682,787

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Summary for Patent: 7,682,787
Title:Compositions and methods for treating disorders associated with abnormal phosphate metabolism
Abstract: The present invention uncovers that mutations in GALNT3 gene encoding UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T3) cause familial tumoral calcinosis (FTC). Methods and pharmaceutical compositions useful for treating disorders associated with abnormal phosphate metabolism are provided. Specifically, inducers of GalNAc-T3 can be used to treat hyperphosphatemia related disorders such as FTC, and on the other hand, inhibitors of GalNAc-T3 can be used to treat disorders associated with hypophosphatemia, such as hypophosphatemic rickets.
Inventor(s): Sprecher; Eli (Kiryat Tivon, IL), Bergman; Reuven (Haifa, IL)
Assignee: Technion Research & Development Foundation Ltd. (Haifa, IL)
Application Number:10/870,030
Patent Claims:see list of patent claims

Details for Patent 7,682,787

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04 ➤ Try a Free Trial Technion Research & Development Foundation Ltd. (Haifa, IL) ➤ Try a Free Trial RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04 ➤ Try a Free Trial Technion Research & Development Foundation Ltd. (Haifa, IL) ➤ Try a Free Trial RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04 ➤ Try a Free Trial Technion Research & Development Foundation Ltd. (Haifa, IL) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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