DrugPatentWatch Database Preview
Patent: 7,645,449
Summary for Patent: 7,645,449
| Title: | Sensitizing cells for apoptosis by selectively blocking cytokines |
| Abstract: | The invention refers to the use of a cytokine antagonist which modulates the expression and/or the function of a cytokine, particularly a Th2 helper cell cytokine, in a cell and causes the down-regulation of anti-apoptotic proteins in said cell through the cytokine modulation for sensitizing cells for apoptosis. In particular, the cells that can be treated with the cytokine antagonists are drug-resistant cancer cells which fail to undergo apoptosis. |
| Inventor(s): | Stassi; Giorgio, N/A (IT-90127 Palermo, IT), Todaro; Matilde, N/A (IT-90127 Palermo, IT) |
| Assignee: | |
| Application Number: | 10/544,794 |
| Patent Claims: | see list of patent claims |
Details for Patent 7,645,449
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Merck | ELSPAR | asparaginase | VIAL | 101063 | 001 | 1978-01-10 | Start Trial | 2023-02-07 | RX | search | ||
| Sigma Tau | ONCASPAR | pegaspargase | VIAL | 103411 | 001 | 1994-02-01 | Start Trial | 2023-02-07 | RX | search | ||
| Genentech | RITUXAN | rituximab | SOLUTION;INTRAVENOUS | 103705 | 001 | 1997-11-26 | Start Trial | 2023-02-07 | RX | search | ||
| Genentech | RITUXAN | rituximab | SOLUTION;INTRAVENOUS | 103705 | 002 | 1997-11-26 | Start Trial | 2023-02-07 | RX | search | ||
| Genentech | HERCEPTIN | trastuzumab | VIAL; INTRAVENOUS | 103792 | 001 | 1998-09-25 | Start Trial | 2023-02-07 | RX | Orphan | search | |
| Genentech Inc | RITUXAN HYCELA | rituximab; hyaluronidase (human recombinant) | SOLUTION;SUBCUTANEOUS | 761064 | 001 | 2017-06-22 | Start Trial | 2023-02-07 | RX | Orphan | search | |
| Genentech Inc | RITUXAN HYCELA | rituximab; hyaluronidase (human recombinant) | SOLUTION;SUBCUTANEOUS | 761064 | 002 | 2017-06-22 | Start Trial | 2023-02-07 | RX | Orphan | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 7,645,449
| Country | Patent Number | Publication Date |
|---|---|---|
| Austria | 396741 | Jun 15, 2008 |
| Australia | 2004210432 | Aug 19, 2004 |
| Australia | 2004210432 | Dec 18, 2008 |
| Canada | 2515302 | Aug 19, 2004 |
| Germany | 602004014103 | Jul 10, 2008 |
| Denmark | 1592449 | Sep 29, 2008 |
| European Patent Office | 1444989 | Aug 11, 2004 |
| >Country | >Patent Number | >Publication Date |
