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Generated: September 23, 2019

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Patent: 7,645,449

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Summary for Patent: 7,645,449
Title:Sensitizing cells for apoptosis by selectively blocking cytokines
Abstract: The invention refers to the use of a cytokine antagonist which modulates the expression and/or the function of a cytokine, particularly a Th2 helper cell cytokine, in a cell and causes the down-regulation of anti-apoptotic proteins in said cell through the cytokine modulation for sensitizing cells for apoptosis. In particular, the cells that can be treated with the cytokine antagonists are drug-resistant cancer cells which fail to undergo apoptosis.
Inventor(s): Stassi; Giorgio, N/A (IT-90127 Palermo, IT), Todaro; Matilde, N/A (IT-90127 Palermo, IT)
Application Number:10/544,794
Patent Claims:see list of patent claims

Details for Patent 7,645,449

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Sign Up 2023-02-07 RX search
Sigma Tau ONCASPAR pegaspargase VIAL 103411 001 1994-02-01 ➤ Sign Up 2023-02-07 RX search
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26 ➤ Sign Up 2023-02-07 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up 2023-02-07 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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