Open chain prolyl urea-related modulators of androgen receptor function
The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula I ##STR00001## wherein R.sub.1, R.sub.2, R.sub.3, X, Y, Z and G are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia, and also provided are pharmaceutical compositions containing such compounds.
Hamann; Lawrence G. (Cherry Hill, NJ), Augeri; David J. (Princeton, NJ), Manfredi; Mark C. (Hamilton, NJ)
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