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Last Updated: January 26, 2021

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Patent: 7,608,261

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Summary for Patent: 7,608,261
Title:VEGF antagonist formulations suitable for intravitreal administration
Abstract: Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has the amino acid sequence shown in SEQ ID NO:4.
Inventor(s): Furfine; Eric (Concord, MA), Dix; Daniel (LaGrangeville, NY), Graham; Kenneth S. (Pleasant Valley, NY), Frye; Kelly (Pomona, NY)
Assignee: Regeneron Pharmacuticals, Inc. (Tarrytown, NY)
Application Number:11/818,463
Patent Claims:see list of patent claims

Details for Patent 7,608,261

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Regeneron Pharmaceuticals EYLEA aflibercept INJECTABLE; INJECTION 125387 001 2011-11-18   Start Trial Regeneron Pharmacuticals, Inc. (Tarrytown, NY) 2039-03-29 RX company
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 7,608,261

Country Patent Number Estimated Expiration
South Africa 200809827   Start Trial
World Intellectual Property Organization (WIPO) 2007149334   Start Trial
United States of America 10400025   Start Trial
United States of America 10464992   Start Trial
United States of America 2007293432   Start Trial
United States of America 2010075903   Start Trial
United States of America 2011257601   Start Trial
>Country >Patent Number >Estimated Expiration

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