Patent: 7,582,618

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Summary for Patent: 7,582,618

Title:	2\'-C-methyl-3\'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
Abstract:	The 3\'-L-valine ester of .beta.-D-2\'-C-methyl-ribofuranosyl cytidine provides superior results against flaviviruses and pestiviruses, including hepatitis C virus. Based on this discovery, compounds, compositions, methods and uses are provided for the treatment of flaviviridae, including HCV, that include the administration of an effective amount of val-mCyd or its salt, ester, prodrug or derivative, optionally in a pharmaceutically acceptable carrier. In an alternative embodiment, val-mCyd is used to treat any virus that replicates through an RNA-dependent RNA polymerase.
Inventor(s):	Sommadossi; Jean-Pierre (Cambridge, MA), LaColla; Paolo (Capoterra, IT), Gosselin; Gilles (Montpellier, FR)
Assignee:	Idenix Pharmaceuticals, Inc. (Cambridge, MA) University of Cagliari (Cagliari, IT) Centre National de la Recherche Scientifique (Paris, FR) L\'Universite Montpellier II (Montpellier, FR)
Application Number:	11/516,928
Patent Claims:	see list of patent claims

Details for Patent 7,582,618

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Biogen Inc.	AVONEX	interferon beta-1a	For Injection	103628	1996-05-17	⤷ Free Forever Trial	2022-06-28
Biogen Inc.	AVONEX	interferon beta-1a	Injection	103628	2003-05-28	⤷ Free Forever Trial	2022-06-28
Biogen Inc.	AVONEX	interferon beta-1a	Injection	103628	2012-02-27	⤷ Free Forever Trial	2022-06-28
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	2002-03-07	⤷ Free Forever Trial	2022-06-28
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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