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Last Updated: December 11, 2019

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Patent: 7,544,772

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Summary for Patent: 7,544,772
Title:Methods for regulating inflammatory mediators and peptides useful therein
Abstract: The present invention includes methods of modulating cellular secretory processes. More specifically the present invention relates to modulating or reducing the release of inflammatory mediators from inflammatory cells by inhibiting the mechanism associated with the release of inflammatory mediators from the vesicles or granules in the inflammatory cells. In this regard, the present invention discloses an intracellular signaling mechanism that illustrates several novel intracellular targets for pharmacological intervention in disorders involving secretion of inflammatory mediators from vesicles in inflammatory cells. MANS peptide and active fragments thereof are useful in such methods.
Inventor(s): Takashi; Shuji (Nagano, JP), Parikh; Indu (Chapel Hill, NC), Adler; Kenneth B. (Raleigh, NC), Martin; Linda D. (Apex, NC), Li; Yuehua (Pearland, TX)
Assignee: Biomarck Pharmaceuticals, Ltd. (Raleigh, NC)
Application Number:11/367,449
Patent Claims:see list of patent claims

Details for Patent 7,544,772

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Biomarck Pharmaceuticals, Ltd. (Raleigh, NC) 2021-06-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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