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Last Updated: July 7, 2020

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Patent: 7,514,594

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Summary for Patent: 7,514,594
Title:Transgenic animal model of bone mass modulation
Abstract: The present invention relates to methods and materials used to express the HBM protein in animal cells and transgenic animals. The present invention also relates to transgenic animals expressing the high bone mass gene, the corresponding wild-type gene, and mutants thereof. The invention provides nucleic acids, including coding sequences, oligonucleotide primers and probes, proteins, cloning vectors, expression vectors, transformed hosts, methods of developing pharmaceutical compositions, methods of identifying molecules involved in bone development, and methods of diagnosing and treating diseases involved in bone development. In preferred embodiments, the present invention is directed to methods for treating, diagnosing and preventing osteoporosis.
Inventor(s): Askew; G. Roger (Boxford, MA), Babij; Philip (Dunstable, MA), Bex, III; Frederick James (Newton Square, PA), Van Nest Bodine; Peter (Havertown, PA)
Assignee: Wyeth (Madison, NJ)
Application Number:10/680,287
Patent Claims:see list of patent claims

Details for Patent 7,514,594

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Wyeth (Madison, NJ) 2039-03-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 7,514,594

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