Patent: 7,507,800

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Summary for Patent: 7,507,800

Title:	Diagnostic test kit for determining a predisposition for breast and ovarian cancer, materials and methods for such determination
Abstract:	The present invention relates generally to the field of human genetics, and more specifically to the detection of a specific type of germline mutations in the BRCA1 gene, which will predispose to breast and ovarian cancer. In addition, the invention relates to the molecular genetic mechanism that may have mediated the genesis of these mutations, in particular the role of Alu repetitive DNA elements present in the intronic regions of BRCA1. The invention further relates to somatic mutations of this type in the BRCA1 gene in human breast and ovarian cancer, and their use in the diagnosis and prognosis of human breast and ovarian cancer. The invention more particularly relates to the screening of this type of BRCA1 mutations in human genomic DNA, which are useful for the diagnosis of inherited predisposition to breast and ovarian cancer.
Inventor(s):	van Ommen; Garrit-Jan Boudewijn (Amsterdam, NL), Petrij-Bos; Anne (Leiden, NL), Bakker; Egbert (Leiden, NL), Devilee; Peter (Leiden, NL)
Assignee:	Rijksuniversiteit te Leiden (Leiden, NL)
Application Number:	10/654,382
Patent Claims:	see list of patent claims

Details for Patent 7,507,800

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source
Schering	INTRON A	interferon alfa-2b	VIAL	103132	003	1986-06-04	➤ Try a Free Trial	Rijksuniversiteit te Leiden (Leiden, NL)	➤ Try a Free Trial	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	002	1986-06-04	➤ Try a Free Trial	Rijksuniversiteit te Leiden (Leiden, NL)	➤ Try a Free Trial	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	001	1986-06-04	➤ Try a Free Trial	Rijksuniversiteit te Leiden (Leiden, NL)	➤ Try a Free Trial	RX		search
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source

International Patent Family for US Patent 7,507,800

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Country	Patent Number	Publication Date
World Intellectual Property Organization (WIPO)	9855650	Dec 10, 1998
United States of America	2005019782	Jan 27, 2005
United States of America	6733966	May 11, 2004
Country	Patent Number	Publication Date

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