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Generated: July 17, 2019

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Patent: 7,501,430

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Summary for Patent: 7,501,430
Title:RAF inhibitors and their uses
Abstract: The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF.sup.V600E. The compounds are useful for the treatment of cell proliferative disorders such as cancer.
Inventor(s): Lapierre; Jean-Marc (Pelham, NH), Namdev; Nivedita D. (Westford, MA), Ashwell; Mark A. (Carlisle, MA), France; Dennis S. (Carlisle, MA), Wu; Hui (Malden, MA), Hutchins; Patrick M. (Denver, CO), Tandon; Manish (Framingham, MA), Liu; Yanbin (Acton, MA), Link; Jeff S. (Londonderry, NH), Ali; Syed M. (North Andover, MA), Brassard; Chris J. (Somerville, MA), Nicewonger; Robb B. (Tyngsboro, MA), Filikov; Anton (Stoneham, MA), Carazza; Rebecca J. (Winchester, MA)
Assignee: ArQule, Inc. (Woburn, MA)
Application Number:11/785,163
Patent Claims:see list of patent claims

Details for Patent 7,501,430

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Sign Up ArQule, Inc. (Woburn, MA) ➤ Sign Up RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26 ➤ Sign Up ArQule, Inc. (Woburn, MA) ➤ Sign Up RX search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18 ➤ Sign Up ArQule, Inc. (Woburn, MA) ➤ Sign Up RX Orphan search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up ArQule, Inc. (Woburn, MA) ➤ Sign Up RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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Fish and Richardson

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