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Generated: August 24, 2019

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Patent: 7,485,297

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Summary for Patent: 7,485,297
Title:Method of inhibition of vascular development using an antibody
Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity and angiogenesis. The agents can be used to treat angiogenesis-associated disorders.
Inventor(s): Wood; Clive R. (Cambridge, MA), Dransfield; Daniel T. (Hanson, MA), Pieters; Henk (Maastricht, NL), Hoet; Rene (Maastricht, NL), Hufton; Simon E. (Clitheroe, GB)
Assignee: Dyax Corp. (Cambridge, MA)
Application Number:11/199,739
Patent Claims:see list of patent claims

Details for Patent 7,485,297

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Sign Up Dyax Corp. (Cambridge, MA) 2023-08-12 RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26 ➤ Sign Up Dyax Corp. (Cambridge, MA) 2023-08-12 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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