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Last Updated: September 21, 2020

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Patent: 7,462,690

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Summary for Patent: 7,462,690
Title:Peptide amidation process
Abstract: The invention provides a process for amidating a desired peptide comprising cleaving a substrate polypeptide at a X.sub.1-cysteine sequence, wherein X1 is the amino acid at the peptide carboxyl-terminus and cysteine is the first amino acid of a palladium cleavage site comprising the sequence cysteine-X2-X3, wherein X2 is any amino acid, X3 is an amino acid selected from the group consisting of cysteine, histidine, or methionine, and wherein the carboxylterminus of the peptide is amidated upon cleavage at the X1-cysteine sequence.
Inventor(s): Holmquist; Barton (Eagle, NE), Strydom; Daniel (Lincoln, NE)
Assignee: Restoragen, Inc. (Lincoln, NE)
Application Number:10/997,081
Patent Claims:see list of patent claims

Details for Patent 7,462,690

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Restoragen, Inc. (Lincoln, NE) 2022-05-24 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Restoragen, Inc. (Lincoln, NE) 2022-05-24 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Restoragen, Inc. (Lincoln, NE) 2022-05-24 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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