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Last Updated: September 22, 2020

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Patent: 7,459,546

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Summary for Patent: 7,459,546
Title:Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase regulatory sequences for gene expression in oleaginous yeast
Abstract: The regulatory sequences associated with the Yarrowia lipolytica glyceraldehyde-3-phosphate dehydrogenase (gpd) and phosphoglycerate mutase (gpm) genes have been found to be particularly effective for the expression of heterologous genes in oleaginous yeast. The promoter regions of the invention, intron and enhancer have been shown to drive high-level expression of genes involved in the production of .omega.-3 and .omega.-6 fatty acids.
Inventor(s): Picataggio; Stephen K. (Landenberg, PA), Zhu; Quinn Qun (West Chester, PA)
Assignee: E.I. du Pont de Nemours and Company (Wilmington, DE)
Application Number:11/183,664
Patent Claims:see list of patent claims

Details for Patent 7,459,546

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial E.I. du Pont de Nemours and Company (Wilmington, DE) 2023-06-25 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial E.I. du Pont de Nemours and Company (Wilmington, DE) 2023-06-25 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial E.I. du Pont de Nemours and Company (Wilmington, DE) 2023-06-25 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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