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Last Updated: December 8, 2021

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Patent: 7,435,869

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Summary for Patent: 7,435,869
Title:Transgenic nonhuman mammals producing fibrinogen in milk and methods of producing fibrin
Abstract: A transgenic, non-human mammalian animal is capable of expressing a heterologous gene for human or other recombinant physiologically functional fibrinogen holoprotein or individual subunit chain polypeptides thereof or a modified or fusion fibrinogen in mammary glands of the animals and secreting the expressed product into a body fluid. Methodology employing such a mammal yields recombinant physiologically functional fibrinogens, subunit chain polypeptides thereof, and modified or fusion fibrinogens.
Inventor(s): Velander; William H. (Blacksburg, VA), Drohan; William N. (Springfield, VA), Lubon; Henryk (Rockville, MD), Johnson; John L. (Blacksburg, VA)
Assignee: Virgina Tech. Intellectual Properties, Inc. (Blacksburg, VA) American National Red Cross (Washington, DC) University of North Carolina at Chapel Hill (Chapel Hill, NC)
Application Number:11/040,117
Patent Claims:see list of patent claims

Details for Patent 7,435,869

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2014-02-18
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2014-02-18
Csl Behring Gmbh RIASTAP fibrinogen concentrate (human) For Injection 125317 2009-01-16 ⤷  Free Forever Trial 2014-02-18
Octapharma Pharmazeutika Produktionsges.m.b.h. FIBRYGA, FIBRYNA fibrinogen (human) For Injection 125612 2017-06-07 ⤷  Free Forever Trial 2014-02-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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