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Last Updated: June 5, 2020

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Patent: 7,432,061

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Summary for Patent: 7,432,061
Title:Assays for measuring matrix metalloproteinase activities
Abstract: Methods for determining matrix metalloproteinase (MMP) activity in biological samples are described. The methods of the invention are useful to assess disease severity or progression, diagnose a particular disease, or develop a profile of MMP activity for inflammatory diseases such as arthritis, or cancer. The methods of the invention involve the use of particular amino acid sequences in substrates to measure the activity in biological samples of MMP\'s including collagenase 3, stromelysin 1, gelatinase A, gelatinase B and collagenase 1. A diagnostic kit for use in determining the amounts of MMP activities in biological samples is also provided.
Inventor(s): Moss; Marcia Lynn (Apex, NC), Rasmussen; Fred H. (Apex, NC), Vitek; Michael P. (Apex, NC)
Assignee: BioZyme, Inc. (Apex, NC)
Application Number:10/449,659
Patent Claims:see list of patent claims

Details for Patent 7,432,061

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial BioZyme, Inc. (Apex, NC) 2022-05-31 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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