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Last Updated: September 28, 2020

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Patent: 7,396,644

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Summary for Patent: 7,396,644
Title:Method of diagnosing and treating dentinogenesis imperfecta type II by using dentin sialophosphoprotein gene and coded product thereof
Abstract: The invention has disclosed a method for diagnosis of dentinogenesis imperfecta type II (DGI-II) and/or dentinogenesis imperfecta type II with deafness (DGI-II with deafness). Said method comprises the steps of detecting the DSPP gene, transcript and/or protein in said subject and comparing it with the normal DSPP gene, transcript and/or protein to determine whether there is any variation, wherein said variation indicates that the possibility of suffering DGI-II and/or DGI-II with deafness in said subject is higher than the normal population. The present invention also discloses the method and pharmaceutical composition for treating DGI-II and/or DGI-II with deafness.
Inventor(s): Kong; Xiangyin (Shanghai, CN), Xiao; Shangxi (Shanghai, CN), Zhao; Guoping (Shanghai, CN), Yu; Chuan (Shanghai, CN), Hu; Landian (Shanghai, CN)
Assignee: Shanghai Institutes of Biological Science, Chinese Academy of Science (Shanghai, CN)
Application Number:10/363,798
Patent Claims:see list of patent claims

Details for Patent 7,396,644

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Shanghai Institutes of Biological Science, Chinese Academy of Science (Shanghai, CN) 2020-09-05 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Shanghai Institutes of Biological Science, Chinese Academy of Science (Shanghai, CN) 2020-09-05 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Shanghai Institutes of Biological Science, Chinese Academy of Science (Shanghai, CN) 2020-09-05 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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