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Last Updated: September 20, 2020

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Patent: 7,375,133

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Summary for Patent: 7,375,133
Title:Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
Abstract: A method for inhibiting and/or ameliorating the occurrence of diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals in a subject whereby a subject is administered a carotenoid analog or derivative, either alone or in combination with another carotenoid analog or derivative, or co-antioxidant formulation. The analog or derivative is administered such that the subject\'s risk of experiencing diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals may be thereby reduced. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include a pharmaceutical composition including a carotenoid analog or derivative. The carotenoid analog may include a conjugated polyene with between 7 to 14 double bonds. The conjugated polyene may include a cyclic ring including at least one substituent. In some embodiments, a cyclic ring of a carotenoid analog or derivative may include at least one substituent. The substituent may be coupled to the cyclic ring with an ether functionality. In some embodiments, a pharmaceutical composition may include a biologically inactive carrier. The pharmaceutical composition may be adapted to be administered to a human subject.
Inventor(s): Lockwood; Samuel Fournier (Lake Linden, MI), O\'Malley; Sean (Honolulu, HI), Watumull; David G. (Honolulu, HI), Hix; Laura M. (San Francisco, CA), Jackson; Henry (Honolulu, HI), Nadolski; Geoff (Kaaawa, HI)
Assignee: Cardax Pharmaceuticals, Inc. (Aiea, HI)
Application Number:10/793,680
Patent Claims:see list of patent claims

Details for Patent 7,375,133

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Cardax Pharmaceuticals, Inc. (Aiea, HI) 2022-07-29 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Cardax Pharmaceuticals, Inc. (Aiea, HI) 2022-07-29 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Cardax Pharmaceuticals, Inc. (Aiea, HI) 2022-07-29 search
Grifols Usa, Llc ALBUTEIN albumin (human) INJECTION, SOLUTION 102478 1 2019-12-15   Start Trial Cardax Pharmaceuticals, Inc. (Aiea, HI) 2022-07-29 search
Grifols Usa, Llc HUMAN ALBUMIN GRIFOLS albumin (human) SOLUTION 103352 1 2003-06-11   Start Trial Cardax Pharmaceuticals, Inc. (Aiea, HI) 2022-07-29 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial Cardax Pharmaceuticals, Inc. (Aiea, HI) 2022-07-29 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial Cardax Pharmaceuticals, Inc. (Aiea, HI) 2022-07-29 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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