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Last Updated: December 5, 2021

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Patent: 7,374,914

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Summary for Patent: 7,374,914
Title:Method of detection of alterations in MSH5
Abstract: We have now discovered that mammals have a DNA gene analogous to that existing in bacteria. MSH5 defects or alterations in this mismatch repair pathway in a mammal, such as a human, can be diagnostic of a predisposition to cancer, and prognostic for a particular cancer: We have discovered and sequenced MSH5 in a number of mammals, including humans. This gene can be used in assays, to express gene product, for drug screens, and therapeutically.
Inventor(s): Kolodner; Richard (San Diego, CA), Winand; Nena (Freeville, NY)
Assignee: Dana-Farber Cancer Institute, Inc. (Boston, MA)
Application Number:10/680,386
Patent Claims:see list of patent claims

Details for Patent 7,374,914

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2017-07-03
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2017-07-03
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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