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Last Updated: December 8, 2021

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Patent: 7,320,872

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Summary for Patent: 7,320,872
Title:Ependymal neural stem cells and method for their isolation
Abstract: The invention relates to an ependymal neural CNS stem cell, which cell expresses the surface protein Notch 1 together with at least one surface protein chosen from the group of Notch 2, Notch 3, CAR (transmembrane protein binding adenovirus) and CFTR cystic fibrosis transmembrane conductance regulator), and which cell also comprises at least one cilium. The invention also relates to preparations, including pharmaceutical preparations, comprising ependymal neural CNS stem cells, in vitro and in vivo assays based thereon and various other uses of the novel ependymal cells according to the invention.
Inventor(s): Janson; Ann Marie (Stockholm, SE), Frisen; Jonas (Stockholm, SE), Johansson; Clas (Stockholm, SE), Momma; Stefan (Spinga, SE), Clarke; Diana (Cambridge, MA), Zhao; Ming (Solna, SE), Lendahl; Urban (Stockholm, SE), Delfani; Kioumars (Solna, SE)
Assignee: NeuroNova AB (Stockholm, SE)
Application Number:10/183,728
Patent Claims:see list of patent claims

Details for Patent 7,320,872

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-05-05 ⤷  Free Forever Trial 2018-06-25
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-12-02 ⤷  Free Forever Trial 2018-06-25
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 2004-10-26 ⤷  Free Forever Trial 2018-06-25
Akorn, Inc. HYDASE hyaluronidase Injection 021716 2005-10-25 ⤷  Free Forever Trial 2018-06-25
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Free Forever Trial 2018-06-25
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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