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Last Updated: October 1, 2020

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Patent: 7,282,567

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Summary for Patent: 7,282,567
Title:Monoclonal antibody hPAM4
Abstract: This invention relates to monovalent and multivalent, monospecific antibodies and to multivalent, multispecific antibodies. One embodiment of these antibodies has one or more identical binding sites where each binding site binds with a target antigen or an epitope on a target antigen. Another embodiment of these antibodies has two or more binding sites where these binding sites have affinity towards different epitopes on a target antigen or different target antigens, or have affinity towards a target antigen and a hapten. The present invention further relates to recombinant vectors useful for the expression of these functional antibodies in a host. More specifically, the present invention relates to the tumor-associated antibody designated PAM4. The invention further relates to humanized and human PAM4 antibodies, and the use of such antibodies in diagnosis and therapy.
Inventor(s): Goldenberg; David M. (Medham, NJ), Hansen; Hans J. (Picayune, MS), Qu; Zhengxing (Warren, NJ)
Assignee: Immunomedics, Inc. (Morris Plains, NJ)
Application Number:10/461,885
Patent Claims:see list of patent claims

Details for Patent 7,282,567

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial Immunomedics, Inc. (Morris Plains, NJ) 2022-06-14 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

McKesson
Express Scripts
AstraZeneca
Harvard Business School
Baxter
Colorcon

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