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Last Updated: November 29, 2021

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Patent: 7,271,143

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Summary for Patent: 7,271,143
Title:Peptides for regulation of urokinase (uPA) and tissue type (tPA) plasminogen activator and method of optimizing therapeutic efficacy
Abstract: Compositions of the polypeptide SEQ ID NO:1, SEQ ID NO:2, anti-LRP antibodies, LRP antagonists, and/or one or more fibrinolytic agents are formulated for enhancing the fibrinolytic activity, reducing the side effects due to vasoactivity caused by the fibrinolytic agents, and/or prolonging the half lives of the fibrinolytic agents. The invention further relates to combination compositions and/or therapy regimens, comprising the polypeptide SEQ ID NO:1 and/or SEQ ID NO:2 and one or more currently used plasminogen activators.
Inventor(s): Higazi; Abd. Al-Roof (Shimshon, IL)
Assignee: Thrombotech Ltd. (Nazareth Illit, IL)
Application Number:10/386,777
Patent Claims:see list of patent claims

Details for Patent 7,271,143

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. ACTIVASE alteplase For Injection 103172 1987-11-13 ⤷  Try it Free 2021-07-10
Genentech, Inc. CATHFLO ACTIVASE alteplase For Injection 103172 2001-09-04 ⤷  Try it Free 2021-07-10
Chiesi Usa, Inc. RETAVASE reteplase For Injection 103786 1996-10-30 ⤷  Try it Free 2021-07-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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