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Last Updated: September 20, 2020

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Patent: 7,211,408

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Summary for Patent: 7,211,408
Title:Recombitope peptides
Abstract: The present invention provides peptides having T cell stimulating activity termed recombitope peptides. Recombitope peptides of the invention preferably comprise at least two T cell epitopes derived from the same or from different protein antigens, and more preferably comprise at least two regions, each region preferably having human T cell stimulating activity and each region comprising at least one T cell epitope derived from a protein antigen. Recombitope peptides of the invention can be derived from protein allergens, autoantigens, or other protein antigens. The invention also provides methods of diagnosing sensitivity to a protein allergen or other protein antigen in an individual, methods to treat such sensitivity and therapeutic compositions comprising one or more recombitope peptides. The invention further provides methods for designing recombitope peptides of the invention where the protein antigen to which the individual is sensitive has unknown or ill-defined T cell epitopes.
Inventor(s): Rogers; Bruce L. (Belmont, MA), Morgenstern; Jay P. (Boston, MA), Bond; Julian F. (Weymouth, MA), Garman; Richard D. (Arlington, MA), Greenstein; Julia L. (West Newton, MA), Kuo; Mei-Chang (Palo Alto, CA), Morville; Malcolm (Shrewsbury, MA)
Assignee: Merck Patent GmbH (Darmstadt, DE)
Application Number:10/463,113
Patent Claims:see list of patent claims

Details for Patent 7,211,408

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Greer Laboratories, Inc. STANDARDIZED MITE DERMATOPHAGOIDES PTERONYSSINUS dermatophagoides pteronyssinus CONCENTRATE 101835 1 2010-02-03   Start Trial Merck Patent GmbH (Darmstadt, DE) 2010-11-02 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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