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Last Updated: November 27, 2021

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Patent: 7,202,075

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Summary for Patent: 7,202,075
Title:Isolated protein having hydroxynitrile lyase activity
Abstract: New genes containing a DNA sequence coding for hydroxynitrile lyase, which genes can be prepared via a primer combination based on the DNA sequence of the 5\'-region of the mdl genes from the Prunus serotina and from Prunus amygdalus and/or a primer 2 based on the 3\'-region of the DNA sequences of one of the hydroxynitrile lyase isoenzymes from Prunus serotina or from Prunus amygdalus, subsequent amplification with a DNA polymerase using a DNA from organisms, containing genes coding for hydroxynitrile lyase, as templates and cloning, and also recombinant proteins which can be prepared in suitable host cells by heterologous expression of the DNA sequence of said HNL genes, and proteins and fusion proteins derived therefrom and use of said proteins for preparing (R)- or (S)-cyanohydrins.
Inventor(s): Schwab; Helmut (Graz, AT), Glieder; Anton (Gleisdorf, AT), Kratky; Christoph (Graz, AT), Dreveny; Ingrid (Graz, AT), Bona; Rodolfo (Graz, AT), Pochlauer; Peter (Linz, AT), Skranc; Wolfgang (Vienna, AT), Mayrhofer; Herbert (Engerwitzdorf, AT), Wirth; Irma (Enns, AT), Neuhofer; Rudolf (Engerwitzdorf, AT)
Assignee: DSM Fine Chemicals Austria NFG GmbH & Co KG (Linz, AT)
Application Number:10/940,954
Patent Claims:see list of patent claims

Details for Patent 7,202,075

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2021-01-16
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2021-01-16
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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