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Last Updated: September 28, 2020

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Patent: 7,179,834

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Summary for Patent: 7,179,834
Title:Salinosporamides and methods for use thereof
Abstract: The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian cells. The CNB392 and CNB476 strains lie within the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by this strain are classified as salinosporamides, and are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC.sub.50 values, high pharmaceutical potency, and selectivity for cancer cells over fungi.
Inventor(s): Fenical; William (Del Mar, CA), Jensen; Paul (San Diego, CA), Mincer; Tracy (San Diego, CA), Feling; Robert H. R. (La Jolla, CA)
Assignee: The Regents of the University of California (Oakland, CA)
Application Number:10/600,854
Patent Claims:see list of patent claims

Details for Patent 7,179,834

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial The Regents of the University of California (Oakland, CA) 2022-06-24 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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