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Last Updated: September 18, 2020

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Patent: 7,163,698

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Summary for Patent: 7,163,698
Title:Controlled drug delivery system using the conjugation of drug to biodegradable polyester
Abstract: The present invention relates to the molecular sustained controlled release system constructed by the conjugation of molecules to be released with biodegradable polyester polymer via covalent bond and method for preparation thereof. In accordance with the present invention, the system may be formulated into microspheres, nanoparticles, or films. The molecular release rate from the above system can be regulated to be proportional to the chemical degradation rate of the biodegradable polyester polymers, resulting in near zero order kinetics profile of release without showing a burst effect. Moreover, the high loading efficiency of hydrophilic drugs can be achieved.
Inventor(s): Oh; Jong Eun (Socho-ku, Seoul, 137-767, KR), Lee; Keon Hyoung (Mapo-ku, Seoul, 121-110, KR), Park; Tae Gwan (Yusong-ku, Taejon-si, 305-390, KR), Nam; Yoon Sung (Songpa-ku, Seoul, 138-789, KR)
Assignee:
Application Number:10/423,536
Patent Claims:see list of patent claims

Details for Patent 7,163,698

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial 2018-05-16 RX search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial 2018-05-16 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial 2018-05-16 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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