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Last Updated: September 18, 2020

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Patent: 7,153,507

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Summary for Patent: 7,153,507
Title:Human antibodies specific for interleukin 15 (IL-15)
Abstract: Isolated human monoclonal antibodies which specifically bind to IL-15 (e.g., human IL-15), and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced in a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
Inventor(s): van de Winkel; Jan G. J. (Zeist, NL), van Dijk; Marcus A. (Bilthoven, NL), Schuurman; Janine (Amsterdam, NL), Gerritsen; Arnout F. (Bunnik, NL), Baadsgaard; Ole (Kyrkogatan, SE)
Assignee: Genmab A/S (Copenhagen, DK)
Application Number:10/226,615
Patent Claims:see list of patent claims

Details for Patent 7,153,507

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial Genmab A/S (Copenhagen, DK) 2039-02-26 RX Orphan search
Immunex ENBREL etanercept VIAL; SUBCUTANEOUS 103795 001 1998-11-02   Start Trial Genmab A/S (Copenhagen, DK) 2039-02-26 RX Orphan search
Immunex ENBREL etanercept SYRINGE 103795 002 1998-11-02   Start Trial Genmab A/S (Copenhagen, DK) 2039-02-26 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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