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Last Updated: September 18, 2020

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Patent: 7,135,305

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Summary for Patent: 7,135,305
Title:Methods for controlling the lysis of coagulated blood with apolipoprotein e4 phenotype
Abstract: Methods for inhibiting lysis of coagulated blood and reducing risk of excessive lysis comprising administration of lysis-inhibiting amounts of apolipoprotein E4, and methods for inhibiting lysis of coagulated blood and reducing risk of excessive lysis comprising administration of a specific level of a lysis-inhibiting agent wherein the specific level is based on the apolipoprotein phenotype of an individual, are provided. Methods for enhancing lysis of coagulated blood by administration of an Apo E peptide fragment to blood containing a clot lysis agent are also provided.
Inventor(s): Broderick; Joseph P. (Cincinnati, OH), Clark; Joseph F. (Cincinnati, OH), Woo; Daniel (Cincinnati, OH)
Application Number:10/398,882
Patent Claims:see list of patent claims

Details for Patent 7,135,305

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Ekr Therap RETAVASE reteplase VIAL 103786 001 1998-05-06   Start Trial 2020-10-13 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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