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Last Updated: October 1, 2020

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Patent: 7,129,210

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Summary for Patent: 7,129,210
Title:Tissue adhesive sealant
Abstract: A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited for bonding tissue alone or in combination with a patch. The ratio between the aldehyde and the amino acid containing species is between 20:1 and 1:1 on an aldehyde moiety:amino acid or peptide subunit molar basis. Particularly strong seals are formed when the protein and cross-linking agent are present in a molar ratio of between 15:1 and 1:1.
Inventor(s): Lowinger; Johan (Dexter, MI), Lowinger; Bruno (Saline, MI), DeLustro; Frank (North Charleston, SC), Cox; David (Woodbury, MN), Browdie; David A. (Scranton, PA)
Assignee: Covalent Medical, Inc. (Ann Arbor, MI)
Application Number:10/894,609
Patent Claims:see list of patent claims

Details for Patent 7,129,210

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bpl ALBUMINEX albumin human SOLUTION 125644 1 2020-05-27   Start Trial Covalent Medical, Inc. (Ann Arbor, MI) 2023-07-23 search
Kedrion S.p.a KEDBUMIN albumin (human) INJECTION, SOLUTION 125384 1 2011-09-15   Start Trial Covalent Medical, Inc. (Ann Arbor, MI) 2023-07-23 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial Covalent Medical, Inc. (Ann Arbor, MI) 2023-07-23 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial Covalent Medical, Inc. (Ann Arbor, MI) 2023-07-23 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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