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Last Updated: July 11, 2020

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Patent: 7,122,177

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Summary for Patent: 7,122,177
Title:Preparation and xenotransplantation of porcine islets
Abstract: The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon xenotransplantation of producing porcine insulin in an appropriate recipient mammal, the method including or comprising the steps of: (I) harvesting the pancreas of piglets at or near full term gestation, and (ii) extracting pancreatic .beta. islet cells from the harvested pancreas wherein the islets (at least at some stage in the performance of the method) are exposed to nicotinamide. Further, the invention relates to a method of encapsulation of a xenotransplantable porcine islet preparation, and transplantation of such a preparation, or a capsule containing such a preparation, into an appropriate recipient mammal.
Inventor(s): Elliott; Robert Bartlett (Auckland, NZ), Calafiore; Riccardo (Perugia, IT), Basta; Gusseppe (Perugia, IT)
Assignee: Diabcell PTY Ltd. (Parkside, AU)
Application Number:09/857,325
Patent Claims:see list of patent claims

Details for Patent 7,122,177

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bpl ALBUMINEX albumin human SOLUTION 125644 1 2020-05-27   Start Trial Diabcell PTY Ltd. (Parkside, AU) 2020-01-20 search
Kedrion S.p.a KEDBUMIN albumin (human) INJECTION, SOLUTION 125384 1 2011-09-15   Start Trial Diabcell PTY Ltd. (Parkside, AU) 2020-01-20 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial Diabcell PTY Ltd. (Parkside, AU) 2020-01-20 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial Diabcell PTY Ltd. (Parkside, AU) 2020-01-20 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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