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Last Updated: September 22, 2020

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Patent: 7,049,406

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Summary for Patent: 7,049,406
Title:Hemoglobin mutants with increased soluble expression and/or reduced nitric oxide scavenging
Abstract: The invention relates to novel recombinant hemoglobins having reduced nitric oxide scavenging and/or increased high soluble expression. The invention further relates to methods of increasing the soluble expression of recombinant hemoglobin by adding exogenous hemin in molar excess of the heme binding sites of recombinant hemoglobin.
Inventor(s): Weickert; Michael J (Belmont, CA), Glascock; Christopher B (Louisville, CO), Mathews; Antony J (Houston, TX), Lemon; Douglas D (Louisville, CO), Doherty; Daniel H (Boulder, CO), Olson; John S (Houston, TX)
Assignee: Baxter Biotech Technology SARL (Neuchatel, CH) William Marsh Rice University (Houston, TX)
Application Number:10/107,871
Patent Claims:see list of patent claims

Details for Patent 7,049,406

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Recordati Rare Diseases, Inc. PANHEMATIN hemin POWDER, FOR SOLUTION 101246 1 1983-07-20   Start Trial Baxter Biotech Technology SARL (Neuchatel, CH) William Marsh Rice University (Houston, TX) 2017-05-02 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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