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Last Updated: December 2, 2021

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Patent: 6,998,137

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Summary for Patent: 6,998,137
Title:Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix
Abstract: The present invention relates to compositions and methods for the modulated release of one or more proteins or peptides. The composition is comprised of a biocompatible polymeric matrix, a protein and/or peptide, and a sparingly water-soluble or essentially insoluble particle. The protein is deposited by adsorption or some other mechanism onto the sparingly water-soluble biocompatible particle wherein the protein-particle combination is dispersed within the polymeric matrix. The deposition of the protein onto the particle acts to modulate the release of the protein or peptide from dosage forms including long-acting dosage systems.
Inventor(s): Shih; Chung (Sandy, UT), Zentner; Gaylen (Salt Lake City, UT), Piao; Ai-Zhi (Salt Lake City, UT)
Assignee: MacroMed, Inc. (Sandy, UT)
Application Number:09/827,100
Patent Claims:see list of patent claims

Details for Patent 6,998,137

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Free Forever Trial 2020-04-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Mallinckrodt
Boehringer Ingelheim
Moodys
Express Scripts
Merck

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