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Generated: September 16, 2019

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Patent: 6,998,137

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Summary for Patent: 6,998,137
Title:Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix
Abstract: The present invention relates to compositions and methods for the modulated release of one or more proteins or peptides. The composition is comprised of a biocompatible polymeric matrix, a protein and/or peptide, and a sparingly water-soluble or essentially insoluble particle. The protein is deposited by adsorption or some other mechanism onto the sparingly water-soluble biocompatible particle wherein the protein-particle combination is dispersed within the polymeric matrix. The deposition of the protein onto the particle acts to modulate the release of the protein or peptide from dosage forms including long-acting dosage systems.
Inventor(s): Shih; Chung (Sandy, UT), Zentner; Gaylen (Salt Lake City, UT), Piao; Ai-Zhi (Salt Lake City, UT)
Assignee: MacroMed, Inc. (Sandy, UT)
Application Number:09/827,100
Patent Claims:see list of patent claims

Details for Patent 6,998,137

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Try a Free Trial MacroMed, Inc. (Sandy, UT) 2020-04-07 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Try a Free Trial MacroMed, Inc. (Sandy, UT) 2020-04-07 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Try a Free Trial MacroMed, Inc. (Sandy, UT) 2020-04-07 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Try a Free Trial MacroMed, Inc. (Sandy, UT) 2020-04-07 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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