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Last Updated: September 22, 2020

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Patent: 6,994,847

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Summary for Patent: 6,994,847
Title:Stabilized interferon compositions
Abstract: Stabilized pharmaceutical formulations comprising IFN-.beta. and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the formation of IFN-.beta. adducts in comparison with IFN-.beta. formulated with mannitol that has not been highly purified. Methods for increasing the stability of IFN-.beta. or a variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided.
Inventor(s): Wolfe; Sidney N. (Lafayette, CA), Hora; Maninder S. (Danville, CA)
Assignee: Chiron Corporation (Emeryville, CA)
Application Number:10/010,448
Patent Claims:see list of patent claims

Details for Patent 6,994,847

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Chiron Corporation (Emeryville, CA) 2020-11-07 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Chiron Corporation (Emeryville, CA) 2020-11-07 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Chiron Corporation (Emeryville, CA) 2020-11-07 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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