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Last Updated: September 21, 2020

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Patent: 6,982,265

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Summary for Patent: 6,982,265
Title:Pyrrolotriazine inhibitors of kinases
Abstract: The present invention provides compounds of formula I ##STR00001## and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Inventor(s): Hunt; John T. (Princeton, NJ), Bhide; Rajeev S. (Langhorne, PA), Borzilleri; Robert Michael (New Hope, PA), Qian; Ligang (Hopewell, NJ)
Assignee: Bristol Myers Squibb Company (Princeton, NJ)
Application Number:09/573,829
Patent Claims:see list of patent claims

Details for Patent 6,982,265

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial Bristol Myers Squibb Company (Princeton, NJ) 2019-05-21 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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