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Last Updated: December 8, 2021

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Patent: 6,982,265

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Summary for Patent: 6,982,265
Title:Pyrrolotriazine inhibitors of kinases
Abstract: The present invention provides compounds of formula I ##STR00001## and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Inventor(s): Hunt; John T. (Princeton, NJ), Bhide; Rajeev S. (Langhorne, PA), Borzilleri; Robert Michael (New Hope, PA), Qian; Ligang (Hopewell, NJ)
Assignee: Bristol Myers Squibb Company (Princeton, NJ)
Application Number:09/573,829
Patent Claims:see list of patent claims

Details for Patent 6,982,265

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 1998-09-25 ⤷  Free Forever Trial 2019-05-21
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 2017-02-10 ⤷  Free Forever Trial 2019-05-21
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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