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Generated: September 19, 2019

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Patent: 6,949,251

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Summary for Patent: 6,949,251
Title: Porous .beta.-tricalcium phosphate granules for regeneration of bone tissue
Abstract:A porous .beta.-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 .mu.m, preferably 50-125 .mu.m. The porous .beta.-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous .beta.-TCP, and a bioactive agent and a binder. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous .beta.-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous .beta.-TCP material and inducing bone formation are also provided.
Inventor(s): Dalal; Paresh S. (Shrewsbury, MA), Dimaano; Godofredo R. (Edison, NJ), Toth; Carol Ann (Sharon, MA), Kulkarni; Shailesh C. (Natick, MA)
Assignee: Stryker Corporation (Kalamazoo, MI)
Application Number:09/960,789
Patent Claims:see list of patent claims

Details for Patent 6,949,251

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23 ➤ Sign Up Stryker Corporation (Kalamazoo, MI) 2021-03-02 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23 ➤ Sign Up Stryker Corporation (Kalamazoo, MI) 2021-03-02 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23 ➤ Sign Up Stryker Corporation (Kalamazoo, MI) 2021-03-02 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23 ➤ Sign Up Stryker Corporation (Kalamazoo, MI) 2021-03-02 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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