Patent: 6,930,090

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Summary for Patent: 6,930,090

Title:	Methods of activating a receptor using amphiphilic drug-oligomer conjugates
Abstract:	The present invention relates to amphiphilic drug-oligomer conjugates capable of traversing the blood-brain barrier (\"BBB\") and to methods of making and using such conjugates. An amphiphilic drug-oligomer conjugate comprises a therapeutic compound conjugated to an oligomer, wherein the oligomer comprises a lipophilic moiety coupled to a hydrophilic moiety. The conjugates of the invention further comprise therapeutic agents such as proteins, peptides, nucleosides, nucleotides, antiviral agents, antineoplastic agents, antibiotics, etc., and prodrugs, precursors, derivatives and intermediates thereof, chemically coupled to amphiphilic oligomers.
Inventor(s):	Ekwuribe; Nnochiri N. (Cary, NC), Radhakrishnan; Balasingam (Chapel Hill, NC), Price; Christopher H. (Chapel Hill, NC), Anderson, Jr.; Wes (Raleigh, NC), Ansari; Aslam M. (Durham, NC)
Assignee:	Nobex Corporation (Durham, NC)
Application Number:	10/716,975
Patent Claims:	see list of patent claims

Details for Patent 6,930,090

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Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	01/10/1978	⤷ Try a Trial	2018-08-14
Nps Pharmaceuticals, Inc.	NATPARA	parathyroid hormone	For Injection	125511	01/23/2015	⤷ Try a Trial	2018-08-14
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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