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Last Updated: January 20, 2020

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Patent: 6,919,350

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Summary for Patent: 6,919,350
Title: Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
Abstract:A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor agonist compound. Preferred examples of such delta receptor agonist compound include diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy for reducing respiratory depression associated with certain analgesics, such as mu opiates.
Inventor(s): Chang; Kwen-Jen (Chapel Hill, NC), McNutt, Jr.; Robert W. (Durham, NC), Pettit; Hugh O. (Cary, NC), Bishop; Michael J. (Durham, NC)
Assignee: Ardent Pharmaceuticals, Inc. (Durham, NC)
Application Number:09/974,004
Patent Claims:see list of patent claims

Details for Patent 6,919,350

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Chiron PROLEUKIN aldesleukin VIAL 103293 001 1992-05-05   Start Trial Ardent Pharmaceuticals, Inc. (Durham, NC) 2013-02-02 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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